I checked the Gamer Loung for an existing thread on this, so I decided to make my own.
Set 15 years after the events of Alien(1979), the game follows Amanda 'Amy' Ripley, daughter of Ellen (Sigourney Weaver), who along with representatives of the Weyland-Yutani Corporation, travel to the Sevastopol Trading Station to recover the black box of the USCSS Nostromo. Upon reaching it however, they find the station heavily damaged and most of the crew missing or dead, and a lone Xenomorph Drone stalking the Sevastopol's decks.
A:I is developed by The Creative Asembly, best known for the Total War series, with the game running on their own in-built engine, and has been in development since 2011. The game is a FPS Survival-Horror/Stealth, in the same vein as Amnesia: The Dark Descent and Outlast (though the game's wiki suggests inspiration from the Bioshock series and Dishonored). While they'll be more than one enemy throughout the game, the focus is to complete misson objectives all the while avoiding attracting the attention of the Alien, which cannot be killed, and will actively seek the player out with adaptive A.I. There's also talk of a 'Crafting System' of sorts that is yet to be elaborated upon.
The trailer (with links) for those who haven't seen it:
While fans of the franchise may approach this installment carefully following the general disappointment of Aliens: Colonial Marines, one must keep in mind that A:CM was produced by a different developer, and for the time being A:I appears to have what it needs to revive the series.
Just be sure to keep a second pair of pants handy.