Kurapika on your sig , he is the original and better Sasuke
About Sakura vs Sasuke, well I think that she could have a chance if she had the byakugou, didn't acted like a pathetic lost kitten near him, and Sasuke was in his Hebi phase
But yeah realistically speaking, she would lose because she simply can't think on her right mind near Sasuke for some stupid reason and Kishimoto never bothered to change it
Kurapika is amazing but Sasuke is better
Yeah, I don't know what drugs Kishi was on to make it so a blind already beaten Sasuke could grab Sakura by her neck and she does nothing about it.
Sakura is alot smarter than sasuke, remember that written chunnin exam?. Both naruto and sasuke cant answer a single questions only sakura can [and without cheating]. Brain/Intelegent "ALWAYS" beat power and speed. If for some god knows why reason sakura vs sasuke happen, my bet is on sakura because she is smarter. She is good at chakra control she even manage to save narutos life with almost zero chakra[The CPR scene]. Yes sasuke is stronger than her by power and speed, but sasuke easly tired especialy when using susanoo and amaterasu, remember when sasuke and edo itachi team up to fight kabuto?. Without itachi sasuke SURELY died. Itachi is smart while sasuke underestimate kabuto and got both of them in trouble. Well thats what i think.
Book Smarts=/=FIght Smarts, she has a terrible fighting style and nope Brain doesn't beat power and speed, you think Shikamaru could beat Madara or Gai? All Sasuke would have to do is fire one Susano'o arrow or use Amaterasu and it would be GG.