If there's a transference of the seal's effects as we saw with Obito, then the person with the accelerated cellular division would be Naruto and Sasuke since it's their bodies' restorative systems that's being stimulated by the jutsu.
There was quite a bit of speculation some time back that was centred around how Sakura was going to bypass this weakness her longevity is normal, it's not biologically extended as Tsunade's because of her Uzumaki heritage. It would have been one method through which she could have surpassed her teacher. Unfortunately, Kishi didn't feel the need to go into depth about Sakura overcoming Tsunade's medical shortcomings like this one.
Good point.
What about if Katsuyu were to come into play, though? Would that have as much of a toll?












