Honestly, no conclusion to any of the pairings would be preferable. Every pairing has something to like. Every pairing also has something to hate. It has nothing to do with the fact that there are "losers" when pairings are defined. It's just that I don't care. None of the pairings have really given me any true reason to support them, but virtually all of them have given reason to be irritated with them in one way or another. And often times, that irritation comes from the fans, even if not from the pairing itself.
I kind of feel the same way, I really don't have a problem with most pairings (except for Sasusaku). It's just the fandoms that bug me. The Naruhina fans bug me because they worship Hinata to much. The Narusaku fans bug me because they keep claiming that everyone (including the anime studio) is against them and are bias against Narusaku, even though everything SEEMS to be going for us (both in anime and manga). Sasusaku fans bug me because they support that pairing for mostly shallow reasons, cute girl gets with handsome guy. Not every fan in their respective fandoms act like that, I'm mostly speaking about the random as the whole.*
But unlike you, I do have a preferred pairing, Narusaku of course. And the reason why I support that pairing is because I see the story going to that direction, and the author MADE me actually care if they get together. So I don't think he will end the series with no one getting together, he took his time building up Naruto and Sakura's relationship throughout his manga. If the series did end without any pairings, or ended with an other pairing for that matter, then what would have been point. What would have been the point of Naruto making the Promise of the Lifetime to Sakura, despite still having a crush on her? What would have been the point of Sai and Yamato's implication that Sakura may have stronger feelings for Naruto? What would have been the point of Sakura's confession, and Naruto's rejection of that confession? What have been the point of the author writing down that Sakura is gaining new feelings for Naruto in the third data book? What would have been the point of the parallels?
So no, I don't think it will end with no pairings. But all I can do is just speculate, and see if I'm right.
*If this consider to be bashing, then I apologize, and I promise I won't do it often. Also, if anyone is offended by it, I apologize for that too. I just wanted to say my opinion.