100% sure. The way the story has been written it is obvious. Whatever limited smoke and mirrors Kishimoto has used to feign possibilities of SS and NH, they are just that -- smoke and mirrors with zero substance.
Could Kishimoto sacrifice 12+ years of work and his credibility just to taser his reading audience at the last minute? Yes, but despite how some people trash and revile his accomplishments because they prefer to focus on the flaws he does legitimately reveal at times, I believe Kishimoto has more integrity as a professional and storyteller than to resort to soap opera nonsense to resolve the hero's romantic life -- all in a way that is unfavorable to the wishes of the hero.
I don't see it happening.
Heh, "smoke and mirrors" I like that. XD
When someone asks me why all the NH focus if NH isn't endgame, I simply respond, "Of course it's convincing, the author is trying to trick you. He doesn't want you to see the final pairings til the very end. However, he did leave a trail of breadcrumbs for the more savvy fans who are willing to follow them."
People think I'm a troll when I say that but I'm dead serious. It's the same thing that happened with Tobi = Obito. We were so convinced that there was no possible way, the author had pulled the wool over our eyes. I don't see why he wouldn't try that with the romantic subplot as well.