I'm going to play devil's advocate and say that we won't see Sakura. Considering Kishi's general treatment of her since this war began, there's a possibility that we won't even see her reaction. If she does receive some panel time it will be alongside the other Rookies. I do suspect that there will be some tears shed from at least one character though.
Madara may react to Naruto's desperate situation. Black Zetsu may use the resulting confusion to his advantage and have the left Rinnegan eye transferred to Madara.