I agree with dovah, had a medic been on hand to stablise her following Kurama's removal, I strongly reckon that Kushina could've survived that night. I feel It was only because she, Minato and Naruto were too far away for backup to arrive on time, that she suggested that Minato seal Kurama back inside her. Of course, being run through by Kurama's claws certainly sealed her fate (no pun intended), but had that not happened, I'm sure she would've lived had a medic been available. It's for the same reasons above that I think, were Naruto to lose Kurama in this battle, if he is pulled away from the fight and tended to by a medic (Sakura?), he would eventually pull through (though I reckon he'd be out of it for a while as his body recovers from the trauma).
And although large chakra reserves aren't necessarily unique traits (many characters can boast of it), the Uzumaki's vitality and longevity is strongly attributed to their close relations with the Senju, making them too direct descendents of the Sage of Six Paths, the first jinchuuriki. It's this heritage that has so far explained why Kushina Uzumaki is the only jinchuuriki shown to have survived the intial extraction process so far. No other jinchuuriki has been shown to be related to the Sage thus far (with the exception of the Gold and Silver brothers who were at best psuedo-jinchuuriki, and even then their ancestry was only speculated).
The only problem is that Obito used a different extraction technique on Kushina, remember it took all nine members of the Akatsuki three days to extract Shukaku from Gaara, between the stress and pain of the process and the dehydration form not only the three days it took to extract but however long it took to get him there, even a Uzumaki would die due to the dehydration (A human can only do three days without water).
I'd like to ask if anyone has seen this pic before:

Was this drawn for a databook or something?? was it released between Part I & II?? because if it was, then Kishi planned this since WAAAYYYY back and it was not just some stupid asspull. Seriously, look at how Obito & Kakashi's positions are totally flipped. If it was intended to be a straight parallel, then Obito would've been in Naruto's place while Kakashi would've been in Sasuke's place. The amount of foreshadowing here is insane, folks.
And this foreshadowing relates to the current topic of Sakura's role as well. If Kishi planned out Obito & Kakashi's story since way back when, then that means he has a big plan regarding Sakura's role in the Naruto vs Sasuke battle. We know that Rin has an extremely vital role to the manga, especially regarding Kakashi vs Obito. If Rin has been given such a large role, then what would that make of Sakura?? interesting to think about.
Can't see the image.
cant see your image
@Jake
when a person's chakra reachs 0 the person dies.
Kurama was extracted from kushina, she survives but it takes away a huge amount of her chakra, she would survive but she had only chakra left to seal the kyuubi within her body and die shortly after because she would run out of chakra.
she wanted to do it to ensure that both her husband and naruto live, but minato wanted to kushina stay alive with naruto because he said there were things that only a mother can say to naruto, the problem was because kyuubi saw this and attacked naruto and so they had to "use" their bodies to protect naruto, the rest you know of.


Notice that this happened before Kushina was impaled.
If Kushina was going to survive then Minato sure as hell didn't know.